Search on: UBIQUITIN-PROTEIN LIGASES 
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Descriptor English:   Ubiquitin-Protein Ligases 
Descriptor Spanish:   Ubiquitina-Proteína Ligasas 
Descriptor Portuguese:   Ubiquitina-Proteína Ligases 
Synonyms English:   Ubiquitin-Protein Ligase  
Tree Number:   D08.811.464.938.750
Definition English:   A diverse class of enzymes that interact with UBIQUITIN-CONJUGATING ENZYMES and ubiquitination-specific protein substrates. Each member of this enzyme group has its own distinct specificity for a substrate and ubiquitin-conjugating enzyme. Ubiquitin-protein ligases exist as both monomeric proteins multiprotein complexes. 
Indexing Annotation English:   UBIQUITIN-PROTEIN LIGASE COMPLEXES is also available
History Note English:   2004; use UBIQUITIN-PROTEIN LIGASE (NM) 1983-2003 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   38183 
Unique Identifier:   D044767 

Occurrence in VHL:
 

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